Asymmetric transformations via C-C bond cleavage.

摘要: Catalytic asymmetric transformations operating by carbon–carbon (C–C) bonds cleavages have emerged as intriguing strategies to access transient organometallic species from different reaction pathways. The reactions and the applicable substrate range expanded considerably over last decade. This overview covers main developments in this field. A major focus is placed on β-carbon eliminations of strained tert-alcohols related processes which been shown be particularly versatile a broad transformations. Furthermore, exciting based direct oxidative C–C bond insertion reactions, for instance into acyl ketones or C–CN nitriles, are discussed.