The importance of the ionic product for water to understand the physiology of the acid-base balance in humans.

摘要: Human plasma is an aqueous solution that has to abide by chemical rules such as the principle of electrical neutrality and constancy ionic product for water. These define acid-base balance in human body. According electroneutrality principle, be electrically neutral sum its cations equals anions. In addition, water constant. Therefore, concentration hydrogen ions depends on composition. Variations alter relative proportion anions predictably lead a change driving adaptive adjustments ionization allow while maintaining constant The accumulation out induces imbalance compensated fall hydroxide brings about rise (acidosis). By contrast, deficiency chloride sodium generates alkalosis increasing ions. adjustment bicarbonate these changes important compensatory mechanism protects pH from severe deviations.