In Silico Design of a Poly-epitope Vaccine for Urinary Tract Infection Based on Conserved Antigens by Modern Vaccinology
作者： Maryam Javadi , Mana Oloomi , Saeid Bouzari
DOI: 10.1007/S10989-020-10137-0
关键词:
摘要: Immunoinformatics or vaccine informatics focuses on applying computational approaches to advance research and development (RD reverse translation codon optimization; second third structure predictions were utilized for both candidates. Finally, the designed constructs with particular conserved epitopes linkers carriers structurally approved. These candidates could be used as a broad immune system inducer, its cross-protective immunity in UTI would confirm future.
springer.com
sci-hub.st 参考文章(48)
Marc R. Wilkins, Elisabeth Gasteiger, Amos Bairoch, Jean-Charles Sanchez, Keith L. Williams, Ron D. Appel, Denis F. Hochstrasser, Protein identification and analysis tools in the ExPASy server Methods of Molecular Biology. ,vol. 112, pp. 531- 552 ,(1999) , 10.1385/1-59259-584-7:531
Yu Xue, Zexian Liu, Jun Cao, Jian Re, Computational Prediction of Post-Translational Modification Sites in Proteins InTech. ,(2011) , 10.5772/18559
Derek T. O’Hagan, Christopher B. Fox, New generation adjuvants – From empiricism to rational design Vaccine. ,vol. 33, ,(2015) , 10.1016/J.VACCINE.2015.01.088
Steven B. Mizel, John T. Bates, Flagellin as an Adjuvant: Cellular Mechanisms and Potential Journal of Immunology. ,vol. 185, pp. 5677- 5682 ,(2010) , 10.4049/JIMMUNOL.1002156
Yongqun He, Zhiwei Cao, Anne S De Groot, Vladimir Brusic, Christian Schönbach, Nikolai Petrovsky, Computational vaccinology and the ICoVax 2012 workshop BMC Bioinformatics. ,vol. 14, pp. 1- 6 ,(2013) , 10.1186/1471-2105-14-S4-I1
Jing Wang, Yabin Yu, Yunan Zhao, Dabing Zhang, Jing Li, Evaluation and integration of existing methods for computational prediction of allergens BMC Bioinformatics. ,vol. 14, pp. 1- 9 ,(2013) , 10.1186/1471-2105-14-S4-S1
D. G. Moriel, I. Bertoldi, A. Spagnuolo, S. Marchi, R. Rosini, B. Nesta, I. Pastorello, V. A. M. Corea, G. Torricelli, E. Cartocci, S. Savino, M. Scarselli, U. Dobrindt, J. Hacker, H. Tettelin, L. J. Tallon, S. Sullivan, L. H. Wieler, C. Ewers, D. Pickard, G. Dougan, M. R. Fontana, R. Rappuoli, M. Pizza, L. Serino, Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 9072- 9077 ,(2010) , 10.1073/PNAS.0915077107
R. A. Laskowski, M. W. MacArthur, D. S. Moss, J. M. Thornton, PROCHECK: a program to check the stereochemical quality of protein structures Journal of Applied Crystallography. ,vol. 26, pp. 283- 291 ,(1993) , 10.1107/S0021889892009944
Tayebeh Farhadi, Navid Nezafat, Younes Ghasemi, Zeinab Karimi, Shiva Hemmati, Nasrollah Erfani, Designing of Complex Multi-epitope Peptide Vaccine Based on Omps of Klebsiella pneumoniae : An In Silico Approach International Journal of Peptide Research and Therapeutics. ,vol. 21, pp. 325- 341 ,(2015) , 10.1007/S10989-015-9461-0
Sujin Lee, Minh Trang Nguyen, Recent Advances of Vaccine Adjuvants for Infectious Diseases Immune Network. ,vol. 15, pp. 51- 57 ,(2015) , 10.4110/IN.2015.15.2.51