Screening for intestinal helminth infestation in a semi-urban cohort of HIV-infected people in Uganda: a combination of techniques may enhance diagnostic yield in the absence of multiple stool samples.

摘要: Intestinal helminth prevalence is best determined by using multiple stool samples from each subject, but this may be difficult in the clinic or hospital setting. We used a range of well-established parasitological techniques study interactions between infestation and HIV cohort 412 HIV-infected people Entebbe, Uganda. Analysis single sample underestimated prevalence, especially low-intensity infections, combination Kato-Katz smear, formol-ether concentration (FEC), charcoal culture for Strongyloides serum enzyme-linked immunosorbent assay Schistosoma mansoni antigen (CAA) increased diagnostic yield. Helminths were diagnosed 23% patients FEC alone, 35% Kato-Katz, 39% FEC, 49% all three tests plus CAA. Performing on enhance detection parasites. Techniques vary their sensitivity different helminths so appropriate choice depends which parasite species are being sought.