Secondary tumors of the gastrointestinal tract: surgical pathologic findings and comparison with autopsy survey.

摘要: Secondary tumors of the gastrointestinal (GI) tract are unusual but probably more common than clinically suspected. Comparison surgical pathologic findings and autopsy experience over a 14-yr period revealed different spectrum tumors, which may reflect clinical practice issues pathophysiology individual tumors. Seventy-three resection or biopsy cases with evident secondary were compared 108 malignancies involving GI tract. The most in specimens melanoma (22 cases), ovary (11 bladder (eight breast (six lung (five cases). primary at (21 gynecologic (18 (14 pancreas (nine In cases, routine histologic examination yielded clues to tumor. Metastatic carcinoma had high potential for misinterpretation because metastases consisted infiltrating strands pleomorphic cells without gland formation. Signet ring present (all six seven 14 autopsies), regardless type carcinoma. time from diagnosis tumor development involvement varied widely, presentation 30 yr metastatic malignant melanoma. Survival after was generally poor, patients surviving less 1 yr. However, long-term palliation be achieved small subset patients, chiefly those single bowel deposits responsive tamoxifen.