Bioactive materials in gene therapy
作者： X.-Z. Zhang , X. Zeng , Y.-X. Sun , R.-X. Zhuo
DOI: 10.1533/9780857092939.2.179
关键词:
摘要: Abstract: Gene therapy is a new form of molecular medicine to cure the inherited or acquired diseases through delivering therapeutic genes targeted cells and replacing disorder genes. Nowadays, large numbers non-viral gene vectors, including cationic liposomes polycations, have attracted much attention due their lower immune response, simpler preparation greater stability as compared with viral vectors. Based on concise introduction cell biology, this chapter reviews most significant delivery systems, introduces current strategies for in vitro vivo .
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sci-hub.se 参考文章(92)
M. Movassagh, D.J. Vara, Gavin Brooks, Gene therapy for the treatment of cardiovascular diseases The Pharmaceutical Press. ,(2002)
G.Y. Wu, C.H. Wu, Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. Journal of Biological Chemistry. ,vol. 262, pp. 4429- 4432 ,(1987) , 10.1016/S0021-9258(18)61209-8
E. Marshall, CLINICAL TRIALS:Gene Therapy Death Prompts Review of Adenovirus Vector Science. ,vol. 286, pp. 2244- 2245 ,(1999) , 10.1126/SCIENCE.286.5448.2244
Takuro Niidome, Kanako Nakashima, Hironobu Takahashi, Yasuro Niidome, Preparation of primary amine-modified gold nanoparticles and their transfection ability into cultivated cells. Chemical Communications. ,vol. 10, pp. 1978- 1979 ,(2004) , 10.1039/B406189F
Soo In Kim, Duckhyang Shin, Hyeon Lee, Byung-Yoon Ahn, Yeup Yoon, Meehyein Kim, Targeted delivery of siRNA against hepatitis C virus by apolipoprotein A-I-bound cationic liposomes. Journal of Hepatology. ,vol. 50, pp. 479- 488 ,(2009) , 10.1016/J.JHEP.2008.10.029
Hye Yeong Nam, Kihoon Nam, Hwa Jeong Hahn, Bo Hye Kim, Hyun Jung Lim, Hyun Jin Kim, Joon Sig Choi, Jong-Sang Park, Biodegradable PAMAM ester for enhanced transfection efficiency with low cytotoxicity. Biomaterials. ,vol. 30, pp. 665- 673 ,(2009) , 10.1016/J.BIOMATERIALS.2008.10.013
Yong-beom Lim, Eunji Lee, You-Rim Yoon, Myeong Sup Lee, Myongsoo Lee, Filamentous artificial virus from a self-assembled discrete nanoribbon. Angewandte Chemie. ,vol. 47, pp. 4525- 4528 ,(2008) , 10.1002/ANIE.200800266
Hidetaka Akita, Asako Kudo, Arisa Minoura, Masaya Yamaguti, Ikramy A. Khalil, Rumiko Moriguchi, Tomoya Masuda, Radostin Danev, Kuniaki Nagayama, Kentaro Kogure, Multi-layered nanoparticles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process. Biomaterials. ,vol. 30, pp. 2940- 2949 ,(2009) , 10.1016/J.BIOMATERIALS.2009.02.009
P. L. Felgner, T. R. Gadek, M. Holm, R. Roman, H. W. Chan, M. Wenz, J. P. Northrop, G. M. Ringold, M. Danielsen, Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 7413- 7417 ,(1987) , 10.1073/PNAS.84.21.7413
Kai K. Ewert, Heather M. Evans, Alexandra Zidovska, Nathan F. Bouxsein, Ayesha Ahmad, Cyrus R. Safinya, A columnar phase of dendritic lipid-based cationic liposome-DNA complexes for gene delivery: hexagonally ordered cylindrical micelles embedded in a DNA honeycomb lattice. Journal of the American Chemical Society. ,vol. 128, pp. 3998- 4006 ,(2006) , 10.1021/JA055907H