Central corneal thickness in patients with congenital aniridia.

摘要: Purpose. To compare the mean central corneal thickness (CCT) in patients with congenital aniridia to that of a group age-matched control subjects. The findings specular and confocal microscopy patient are discussed. Methods. values five consecutive pachymetry measurements subjects were used for analysis. Statistical analysis was performed Mann–Whitney rank sum test. Specular on one using Konan Microscope Noncon ROBO CA (Hyogo, Japan). Confocal through focusing Tandem Scanning (Reston, VA). Results. Mean CCT measured 691.8 75.4 m (16 eyes 10 patients) 548.2 21.2 (P0.001). showed normal endothelial cell counts structure. this normal-appearing keratocytes thick stroma. Conclusions. Patients have significantly thicker corneas than do This difference can important implications treatment those who develop secondary glaucoma. increased is not result dysfunction but appears be production thickened otherwise healthy cornea by mutated PAX6 gene.