Evaluation of glucose homeostasis

摘要: Obesity and dyslipidemia are often found in association with insulin resistance (IR). These components combined hypertension characterize the most common endocrine disorder humans, metabolic syndrome. Thus, addition to profiling body weight evolution lipid metabolites, glucose tolerance (a reflection of IR) sensitivity should also be considered as part any phenotyping protocol. The ability measure IR is important not only quest fully understand pathogenesis syndrome mouse, but test effects potential interventions. This unit presents a variety tests used for this purpose, including direct blood measurements, measurement by ELISA, homeostatic model assessment, tests, euglycemic clamp.