What is the impact of SOCS3, IL-35 and IL17 in immune pathogenesis of recurrent pregnancy loss?
作者： Zehra Sema Ozkan , Derya Devecı , Mehmet Sımsek , Fulya Ilhan , Ali Rısvanlı
DOI: 10.3109/14767058.2014.916676
关键词:
摘要: AbstractObjective: To investigate the plasma levels of interleukin-4 (IL-4), IL-6, IL-10, tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), transforming growth factor-beta (TGF-beta), IL-17, IL-35 and suppressor cytokine signaling 3 (SOCS3) in women with history idiopathic recurrent pregnancy loss (RPL) fertile controls.Methods: This study was conducted 60 RPL cases 40 age-matched controls. Mid-follicular IFN-gamma, TNF-alpha, TGF-beta, IL-4, SOCS3 were assayed by an enzyme linked immunosorbent assay.Results: The mean age control 31.6 ± 0.6 32.1 ± 0.7 years, respectively. While group significantly lower than that group; IL-17 TGF-beta higher group. comparison ratios between cont...
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