Predictive factors for erectile dysfunction in men with prostate cancer after brachytherapy: is dose to the penile bulb important?

摘要: Purpose: To determine predictive factors for postimplant erectile dysfunction (ED) in a cohort of patients, according to prospectively collected data; specifically, assess the impact penile bulb volume and D50 D95 (dose covering 50% 95% volume, respectively) on ED. Methods Materials: Three hundred forty-two patients were identified who potent before implant had at least 2 years’ follow-up. Patient, tumor, treatment, dosimetric data all patients. Postimplant ED was defined both physician-documented patient-documented outcome data. Binary logistic regression analysis used create multivariable models predictors 1, 2, 3 years after implant. Results: Physician-documented rates 57%, 48%, 38% implant, respectively. Patient-documented 70% 66% 1 years, Multivariable analyses revealed age degree preimplant function be consistently significant Use hormones 1-year endpoint but not thereafter, keeping with time course testosterone recovery. Penile D50, found any point, contrast previous studies. In addition, planning ultrasound target number needles, institutional case sequence various points, consistent traumatic etiology Conclusions: We no evidence support dosimetry as an independent factor using or outcomes.