Predicting Influenza Infections during Epidemics with Use of a Clinical Case Definition

作者: G. Boivin , I. Hardy , G. Tellier , J. Maziade

DOI: 10.1086/317425

关键词:

摘要: Combined pharyngeal and nasal swab specimens were collected from 100 subjects who presented with a flu-like illness (fever >37.8 degrees C plus 2 of 4 symptoms: cough, myalgia, sore throat, headache) or =38.2 as well 3 the symptoms in clinical case definition. Stepwise logistic regression showed that cough (odds ratio [OR], 6.7; 95% confidence interval [CI], 1.4-34.1; P=.02) fever (OR, 3.1; CI, 1.4-8.0; P=.01) only factors significantly associated positive PCR test for influenza. The predictive value, negative sensitivity, specificity definition including (temperature >38 C) diagnosis influenza infection during this flu season 86.8%, 39.3%, 77.6%, 55.0%, respectively.

参考文章(16)
David P. Calfee, Frederick G. Hayden, New approaches to influenza chemotherapy. Neuraminidase inhibitors. Drugs. ,vol. 56, pp. 537- 553 ,(1998) , 10.2165/00003495-199856040-00003
G P Leonardi, H Leib, G S Birkhead, C Smith, P Costello, W Conron, Comparison of rapid detection methods for influenza A virus and their value in health-care management of institutionalized geriatric patients. Journal of Clinical Microbiology. ,vol. 32, pp. 70- 74 ,(1994) , 10.1128/JCM.32.1.70-74.1994
Gerald L. Mandell, R. Gordon Douglas, John E. Bennett, Principles and Practice of Infectious Diseases ,(1985)
J S Ellis, D M Fleming, M C Zambon, Multiplex reverse transcription-PCR for surveillance of influenza A and B viruses in England and Wales in 1995 and 1996. Journal of Clinical Microbiology. ,vol. 35, pp. 2076- 2082 ,(1997) , 10.1128/JCM.35.8.2076-2082.1997
Ann R. Falsey, John J. Treanor, Robert F. Betts, Edward E. Walsh, Viral Respiratory Infections in the Institutionalized Elderly: Clinical and Epidemiologic Findings Journal of the American Geriatrics Society. ,vol. 40, pp. 115- 119 ,(1992) , 10.1111/J.1532-5415.1992.TB01929.X
John J. Treanor, Frederick G. Hayden, Peter S. Vrooman, Rick Barbarash, Robert Bettis, Dennis Riff, Sudeep Singh, Nelson Kinnersley, Penelope Ward, Roger G. Mills, for the US Oral Neuraminidase Study Group, Efficacy and Safety of the Oral Neuraminidase Inhibitor Oseltamivir in Treating Acute Influenza JAMA. ,vol. 283, pp. 1016- 1024 ,(2000) , 10.1001/JAMA.283.8.1016
Frederick G. Hayden, John J. Treanor, R. Scott Fritz, Monica Lobo, Robert F. Betts, Madeline Miller, Nelson Kinnersley, Roger G. Mills, Penelope Ward, Stephen E. Straus, Use of the oral neuraminidase inhibitor oseltamivir in experimental human influenza: randomized controlled trials for prevention and treatment. JAMA. ,vol. 282, pp. 1240- 1246 ,(1999) , 10.1001/JAMA.282.13.1240
A. R. Falsey, C. K. Cunningham, W. H. Barker, R. W. Kouides, J. B. Yuen, M. Menegus, L. B. Weiner, C. A. Bonville, R. F. Betts, Respiratory Syncytial Virus and Influenza A Infections in the Hospitalized Elderly The Journal of Infectious Diseases. ,vol. 172, pp. 389- 394 ,(1995) , 10.1093/INFDIS/172.2.389
Christine E Long, Caroline B Hall, Coleen K Cunningham, Leonard B Weiner, Kathleen P Alger, Maria Gouveia, Carol B Colella, Kenneth C Schnabel, William H Barker, Influenza surveillance in community-dwelling elderly compared with children Archives of Family Medicine. ,vol. 6, pp. 459- 465 ,(1997) , 10.1001/ARCHFAMI.6.5.459