Extensive Variation in the Density and Distribution of DNA Polymorphism in Sorghum Genomes

摘要: Sorghum genotypes currently used for grain production in the United States were developed from African landraces that imported starting mid-to-late 19th century. Farmers and plant breeders selected with reduced height, early flowering, increased yield, adaptation to drought, improved resistance lodging, diseases pests. DNA polymorphisms distinguish three historically important sorghum genotypes, BTx623, BTx642 Tx7000, characterized by genome sequencing, genotyping genetic mapping, pedigree-based haplotype analysis. The distribution density of sequenced genomes varied widely, part because lines derived through breeding selection diverse Kafir, Durra, Caudatum race accessions. Genomic spanning dw1 (SBI-09) dw3 (SBI-07) had identical haplotypes due height. Lower SNP genes located pericentromeric regions compared euchromatic is consistent background these low recombination. was higher >100-fold contiguous intervals spanned up 300 Kbp. localized variation polymorphism occurred throughout where recombination elevated, however, not correlated gene or methylation. Overall, chromosomes contain distal extensive, density, large diversity,