Alternative splicing: enhancing ability to cope with stress via transcriptome plasticity.

摘要: Alternative splicing is a mechanism for the regulation of gene expression that widespread in higher eukaryotes. Genome-wide approaches, based on comparison expressed and genomic sequences, tiling arrays, next-generation sequencing, have provided growing knowledge extent, distribution association alternative with stress-related genes plants. The functional meaning response to stress has been defined many genes, particular those involved responses, such as protein kinases, transcription factors, regulators pathogen-resistance genes. production proteins diverse domain rearrangements from same main plant abiotic also characterized by second mechanism, which consists transcripts are targeted nonsense-mediated decay. These quantitatively regulate expression. Many events well conserved among species, across kingdoms, especially observed stress, encoding regulators, other classes RNA-binding proteins. Nevertheless, non-conserved indicate represents an evolutionary strategy rapidly increases genome plasticity develops new functions, along mechanisms duplication. Finally, study naturally occurring variability identification regions crops proposed strategies selecting genotypes superior performance under adverse environmental conditions.