Nanoparticle-mediated double-stranded RNA delivery system: A promising approach for sustainable pest management.

作者: Shuo Yan , Bin‐Yuan Ren , Jie Shen

DOI: 10.1111/1744-7917.12822

关键词:

摘要: RNA interference (RNAi) targeting lethal genes in insects has great potential for sustainable crop protection. Compared with traditional double‐stranded (ds) RNA delivery systems, nanoparticles such as chitosan, liposomes, and cationic dendrimers offer advantages in delivering dsRNA/small interfering (si) RNA to improve RNAi efficiency, thus promoting the development and practice of RNAi‐based pest management strategies. Here, we illustrate the limitations of traditional dsRNA delivery systems, reveal the mechanism of nanoparticle …

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