Association between maternal smoking, gender, and cleft lip and palate ,

作者: Daniella Reis Barbosa Martelli , Ricardo D. Coletta , Eduardo A. Oliveira , Mário Sérgio Oliveira Swerts , Laíse A. Mendes Rodrigues

DOI: 10.1016/J.BJORL.2015.07.011

关键词:

摘要: Introduction: Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of face. Objective: To assess relationship between maternal smoking, gender and CL/P. Methods: This is an epidemiological cross-sectional study. We interviewed 1519 mothers divided into two groups: Cases: children with CL/P (n = 843) Controls: without 676). All were classified as smoker or non-smoker subjects during first trimester pregnancy. determine association among gender, CL/P, odds ratios calculated adjustment was made by a logistic regression model. Results: An smoking presence cleft observed. There also strong male (OR 3.51; 95% CI 2.83---4.37). By binary analysis, it demonstrated that both variables independently associated clefts. In multivariate had 2.5- 1.5-time greater chance having cleft, respectively.

参考文章(29)
J.D. Niswander, C.S. Chung, C.J. Maclean, K. Dronamraju, Sex ratio and cleft lip with or without cleft palate. The Lancet. ,vol. 300, pp. 858- 860 ,(1972) , 10.1016/S0140-6736(72)92217-9
Daniella Reis Barbosa Martelli, Kaliany Wanessa da Cruz, Letízia Monteiro de Barros, Marise Fernandes Silveira, Mário Sérgio Oliveira Swerts, Hercílio Martelli Júnior, Maternal and paternal age, birth order and interpregnancy interval evaluation for cleft lip-palate Revista Brasileira De Otorrinolaringologia. ,vol. 76, pp. 107- 112 ,(2010) , 10.1590/S1808-86942010000100018
A. Derijcke, A. Eerens, C. Carels, The incidence of oral clefts: a review British Journal of Oral & Maxillofacial Surgery. ,vol. 34, pp. 488- 494 ,(1996) , 10.1016/S0266-4356(96)90242-9
Andreia Bufalino, Lívia Máris Ribeiro Paranaíba, Sibele Nascimento de Aquino, Hercílio Martelli-Júnior, Mario Sergio Oliveira Swerts, Ricardo D. Coletta, MATERNAL POLYMORPHISMS IN FOLIC ACID METABOLIC GENES ARE ASSOCIATED WITH NONSYNDROMIC CLEFT LIP AND/OR PALATE IN THE BRAZILIAN POPULATION web science. ,vol. 88, pp. 980- 986 ,(2010) , 10.1002/BDRA.20732
Kaare Christensen, Poul Fogh-Andersen, Cleft lip (± cleft palate) in Danish twins, 1970–1990 American Journal of Medical Genetics. ,vol. 47, pp. 910- 916 ,(1993) , 10.1002/AJMG.1320470620
Katamara Rodrigues, Marina Fernandes de Sena, Ângelo Giuseppe Roncalli, Maria Ângela Fernandes Ferreira, Prevalence of orofacial clefts and social factors in Brazil. Brazilian Oral Research. ,vol. 23, pp. 38- 42 ,(2009) , 10.1590/S1806-83242009000100007
Tao Wu, Kung Yee Liang, Jacqueline B. Hetmanski, Ingo Ruczinski, Margaret Daniele Fallin, Roxann G. Ingersoll, Hong Wang, Shangzhi Huang, Xiaoqian Ye, Yah-Huei Wu-Chou, Philip K. Chen, Ethylin W. Jabs, Bing Shi, Richard Redett, Alan F. Scott, Terri H. Beaty, Evidence of gene–environment interaction for the IRF6 gene and maternal multivitamin supplementation in controlling the risk of cleft lip with/without cleft palate Human Genetics. ,vol. 128, pp. 401- 410 ,(2010) , 10.1007/S00439-010-0863-Y
Min Shi, Kaare Christensen, Clarice R. Weinberg, Paul Romitti, Lise Bathum, Anthony Lozada, Richard W. Morris, Michael Lovett, Jeffrey C. Murray, Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants American Journal of Human Genetics. ,vol. 80, pp. 76- 90 ,(2007) , 10.1086/510518
Maria Jentink, Janneke, Loane, Jane K Dolk, Helen, Barisic, Ingeborg, Garne, Ester, C de Jong-van den Berg Lolkje TW for the EUROCAT, Vera Nelen, B Khoshnood, B Doray, S Poetzsch, Awi Wiesel, M O’Mahony, Anna Pierini, Gatt Rivieri, F, Valproic Acid Monotherapy in Pregnancy and Major Congenital Malformations The New England Journal of Medicine. ,vol. 362, pp. 2185- 2193 ,(2010) , 10.1056/NEJMOA0907328