作者: Daniella Reis Barbosa Martelli , Ricardo D. Coletta , Eduardo A. Oliveira , Mário Sérgio Oliveira Swerts , Laíse A. Mendes Rodrigues
DOI: 10.1016/J.BJORL.2015.07.011
关键词:
摘要: Introduction: Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of face. Objective: To assess relationship between maternal smoking, gender and CL/P. Methods: This is an epidemiological cross-sectional study. We interviewed 1519 mothers divided into two groups: Cases: children with CL/P (n = 843) Controls: without 676). All were classified as smoker or non-smoker subjects during first trimester pregnancy. determine association among gender, CL/P, odds ratios calculated adjustment was made by a logistic regression model. Results: An smoking presence cleft observed. There also strong male (OR 3.51; 95% CI 2.83---4.37). By binary analysis, it demonstrated that both variables independently associated clefts. In multivariate had 2.5- 1.5-time greater chance having cleft, respectively.