Nitric oxide and redox signaling in allergic airway inflammation.
作者： Niki L. Reynaert , Karina Ckless , Emiel F.M. Wouters , Albert Van Der Vliet , Yvonne M.W. Janssen-Heininger
关键词:
摘要: A number of diseases the respiratory tract, as exemplified in this review by asthma, are associated with increased amounts nitric oxide (NO) expired breath. Asthma is furthermore characterized production reactive oxygen species that scavenge NO to form more nitrogen demonstrated enhanced presence nitrated proteins lungs these patients. This oxidative metabolism leaves less bioavailable and coincides lower S-nitrosothiols. In review, we speculate on mechanisms responsible for inflammatory airway disease discuss apparent paradox higher levels opposed decreased We will give an overview regulation biochemical events which transduces signals into cellular responses, a particular focus modulation inflammation NO. Lastly, difficulties studying signaling possible...
liebertonline.com 
core.ac.uk 参考文章(173)
J. P. Eiserich, A. G. Estevez, T. V. Bamberg, Y. Z. Ye, P. H. Chumley, J. S. Beckman, B. A. Freeman, Microtubule dysfunction by posttranslational nitrotyrosination of α-tubulin: A nitric oxide-dependent mechanism of cellular injury Proceedings of the National Academy of Sciences of the United States of America. ,vol. 96, pp. 6365- 6370 ,(1999) , 10.1073/PNAS.96.11.6365
Harvey E. Marshall, Jonathan S. Stamler, Nitrosative Stress-induced Apoptosis through Inhibition of NF-κB Journal of Biological Chemistry. ,vol. 277, pp. 34223- 34228 ,(2002) , 10.1074/JBC.M201638200
Solange H. Korn, Emiel F. M. Wouters, Nanda Vos, Yvonne M. W. Janssen-Heininger, Cytokine-induced Activation of Nuclear Factor-κB Is Inhibited by Hydrogen Peroxide through Oxidative Inactivation of IκB Kinase * Journal of Biological Chemistry. ,vol. 276, pp. 35693- 35700 ,(2001) , 10.1074/JBC.M104321200
E.B. Spector, S.C.H. Rice, S. Moedjono, B. Bernard, S.D. Cederbaum, Biochemical properties of arginase in human adult and fetal tissues. Biochemical Medicine. ,vol. 28, pp. 165- 175 ,(1982) , 10.1016/0006-2944(82)90067-9
Misato Kashiba-Iwatsuki, Makiko Yamaguchi, Masayasu Inoue, Role of ascorbic acid in the metabolism of S
-nitroso-glutathione FEBS Letters. ,vol. 389, pp. 149- 152 ,(1996) , 10.1016/0014-5793(96)00560-1
Sankar Ghosh, Michael Karin, Missing Pieces in the NF-κB Puzzle Cell. ,vol. 109, pp. S81- S96 ,(2002) , 10.1016/S0092-8674(02)00703-1
Kirkwood A Pritchard, Allan W Ackerman, Eric R Gross, David W Stepp, Yang Shi, Jason T Fontana, John E Baker, William C Sessa, None, Heat Shock Protein 90 Mediates the Balance of Nitric Oxide and Superoxide Anion from Endothelial Nitric-oxide Synthase Journal of Biological Chemistry. ,vol. 276, pp. 17621- 17624 ,(2001) , 10.1074/JBC.C100084200
Hai-Bing Peng, Peter Libby, James K. Liao, Induction and Stabilization of IκBα by Nitric Oxide Mediates Inhibition of NF-κB Journal of Biological Chemistry. ,vol. 270, pp. 14214- 14219 ,(1995) , 10.1074/JBC.270.23.14214
José M. Souza, Irene Choi, Qiping Chen, Marie Weisse, Evgueni Daikhin, Marc Yudkoff, Martin Obin, Jahan Ara, Joel Horwitz, Harry Ischiropoulos, Proteolytic Degradation of Tyrosine Nitrated Proteins Archives of Biochemistry and Biophysics. ,vol. 380, pp. 360- 366 ,(2000) , 10.1006/ABBI.2000.1940
Young Y. Koh, Richard Dupuis, Mary Pollice, Kurt H. Albertine, James E. Fish, Stephen P. Peters, Neutrophils Recruited to the Lungs of Humans by Segmental Antigen Challenge Display a Reduced Chemotactic Response to Leukotriene B4 American Journal of Respiratory Cell and Molecular Biology. ,vol. 8, pp. 493- 499 ,(1993) , 10.1165/AJRCMB/8.5.493