The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients.

摘要: The periodontal health of 30 adult epileptic patients treated with either sodium valproate or phenytoin was compared a control group (n = 15) otherwise healthy patients. 3 groups were matched for age and sex. Patients on therapy showed significantly higher plaque scores (P less than 0.05), gingival index 0.05) pocketing in the group. % hyperplasia phenytoin-treated those However, had bone loss 0.01). No significant differences observed between any parameters assessed. results from this study would suggest that has no unwanted effects may be considered safe alternative, regarding aspects, to treatment onset epilepsy.