Ultrastructure of cortisol-secreting adrenal adenomata.

摘要: Two adrenocortical adenomata causing Cushing's syndrome were examined by electron microscopy. Adenomatous cells arranged in islets and contained ovoid nuclei with a prominent nucleoli. Mitochondria polymorphic displayed tubular lamelliform cristae. Some apparently devoid of lipid droplets possessed an exceedingly well developed SER, the tubules which intermingled small stacks ribosome-studded cisternae, while other parenchymal large clumps scanty SER tubules. A conspicuous Golgi apparatus many dense bodies probable lysosomal nature also observed. These findings suggest that are derived from zona fasciculata lipid-laden lipid-free are, respectively, resting actively secreting elements.