Effect of intrarenal furosemide on renal function and intrarenal hemodynamics in acute renal failure

摘要: The ability of short-term furosemide administration to alter intrarenal hemodynamics and modify the clinical course acute renal failure was assessed in six patients 2 9 days after onset failure. Following arterial catheterization, intraarterial at a dose 9.6 mg/min for 30 minutes failed improve function as either by an increase urine output or decrease serum creatinine during 4 five oliguric patients. In sixth patient with nonoliguric failure, volume increased gradual blood urea nitrogen week study. Furosemide mean flow its distribution determined intervals 3 40 infusion. These studies demonstrate that large doses does not established