Association of metabolic syndrome with falls in patients with Parkinson's disease

作者: Alice Laudisio , Maria Rita Lo Monaco , Davide L Vetrano , Maria Stella Pisciotta , Anna Rita Bentivoglio

DOI: 10.1016/J.CLNU.2016.02.004

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摘要: Summary Background & aims Falls are a major threat for patients with Parkinson's disease, as they associated higher risk of morbidity, loss functional ability, institutionalization, and mortality. Metabolic syndrome (MetS) is poorer physical performance in middle age, but its impact the older frailer subjects unclear. The present study aimed at assessing association MetS falls disease. Methods We analyzed data 194 elderly disease attending geriatric Day Hospital. History that occurred over last year, well number falls, were recorded. was diagnosed according to National Cholesterol Education Program's ATP-III criteria. Results reported by 91 participants (47%). Logistic regression analysis showed reduced occurrence (OR = .26; 95% CI = .10–.69; P = .007). Also, among who fell, Poisson indicated predicted (IRR = .43; CI = .20–.89; P = .024). Conclusions In our population probability falls; falls. Dedicated studies needed better understand subsystems involved, therapeutic implications such an association.

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