Composition and method for cancer treatment

作者: Daruka Mahadevan

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摘要: Anti-CEACAM6 antibodies and antibody fragments, nucleic acids encoding them, methods of their manufacture, to treat cancer using these compounds are provided.

参考文章(56)
William R. Pearson, Flexible sequence similarity searching with the FASTA3 program package. Methods of Molecular Biology. ,vol. 132, pp. 185- 219 ,(2000) , 10.1385/1-59259-192-2:185
Christine A. Iacobuzio-Donahue, Byungwoo Ryu, Ralph H. Hruban, Scott E. Kern, Exploring the Host Desmoplastic Response to Pancreatic Carcinoma: Gene Expression of Stromal and Neoplastic Cells at the Site of Primary Invasion American Journal of Pathology. ,vol. 160, pp. 91- 99 ,(2002) , 10.1016/S0002-9440(10)64353-2
H.D. Edington, C.D. Kowal, M. Unger, G. Levine, S.A. Yousem, C.G. Watson, W.N. Tauxe, Radioimmunoimaging of metastatic medullary carcinoma of the thyroid gland using an indium-111-labeled monoclonal antibody to CEA. Surgery. ,vol. 104, pp. 1004- ,(1988)
Ralph H. Hruban, Giovanni Parmigiani, Jessa Jones, Scott E. Kern, Natalie J. Blades, Byungwoo Ryu, Michael A. Hollingsworth, Relationships and Differentially Expressed Genes among Pancreatic Cancers Examined by Large-scale Serial Analysis of Gene Expression Cancer Research. ,vol. 62, pp. 819- 826 ,(2002)
Elizabeth M. Jaffee, Ralph H. Hruban, Tara Ellingham, Karen M. Hauda, Patricia P. Long, Charles J. Yeo, Constance A. Griffin, Stefan K. Bohlander, Laura A. Morsberger, Consistent Chromosome Abnormalities in Adenocarcinoma of the Pancreas Cancer Research. ,vol. 55, pp. 2394- 2399 ,(1995)
H. Friess, J. Ding, J. Kleeff, L. Fenkell, J. A. Rosinski, A. Guweidhi, J. F. Reidhaar-Olson, M. Korc, J. Hammer, M. W. Büchler, Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer Cellular and Molecular Life Sciences. ,vol. 60, pp. 1180- 1199 ,(2003) , 10.1007/S00018-003-3036-5
Malik Juweid, Jerry Shevitz, Lawrence C. Swayne, David M. Goldenberg, Rosalyn D. Blumenthal, Shui-on Leung, Robert Dunn, Robert M. Sharkey, Jeffry A. Siegel, Gary L. Griffiths, Thomas Behr, George Y. Wong, Hans J. Hansen, Evaluation of a Complementarity-Determining Region-Grafted (Humanized) Anti-Carcinoembryonic Antigen Monoclonal Antibody in Preclinical and Clinical Studies Cancer Research. ,vol. 55, ,(1995)
Yoshinori Satow, Gerson H. Cohen, Eduardo A. Padlan, David R. Davies, Phosphocholine binding immunoglobulin Fab McPC603: An X-ray diffraction study at 2.7 Å Journal of Molecular Biology. ,vol. 190, pp. 593- 604 ,(1985) , 10.1016/0022-2836(86)90245-7