Functions and targets of let-7 micro rnas

作者: Frank J. Slack , Kevin Kelnar , Mike W. Byrom , Andreas G. Bader , David Brown

DOI:

关键词:

摘要: The present invention concerns methods and compositions for treating or assessing treatment of diseases related to mis-expression genes genetic pathways that can be modulated by let-7. Methods may include evaluating patients let-7, and/or using an expression profile assess the condition a patient with appropriate miRNA.

参考文章(115)
Stanley T. Crooke, Oligoribonucleotides for cleaving RNA ,(1996)
Richard Winneker, Zhiming Zhang, Deepak Sampath, Cyr61 as a target for treatment and diagnosis of breast cancer ,(2001)
Charles-Henri Lecellier, Olivier Voinnet, Michel Lanotte, Anne Saumet, Identification and use of mirnas for differentiating myelogenous leukaemia cells ,(2005)
Chenghua Liu, Sei-Yu Chen, Yongming Sun, Herve Recipon, Compositions and methods relating to prostate specific genes and proteins ,(2001)
J. William Efcavitch, Lincoln John Mcbride, William Alexander Andrus, Chemical capping by phosphitylation during oligonucleotide synthesis ,(1988)
Bret Taback, Dave S.B. Hoon, DNA markers for management of cancer ,(2004)
Sandrine Hamels, Jose Remacle, Francois de Longueville, Detection and quantification of siRNA on micro-arrays ,(2004)