Impact of Physical Activity on Cancer Recurrence and Survival in Patients With Stage III Colon Cancer: Findings From CALGB 89803

作者: Jeffrey A. Meyerhardt , Denise Heseltine , Donna Niedzwiecki , Donna Hollis , Leonard B. Saltz

DOI: 10.1200/JCO.2006.06.0863

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摘要: Purpose Regular physical activity reduces the risk of developing colon cancer, however, its influence on patients with established disease is unknown. Patients and Methods We conducted a prospective observational study 832 stage III cancer enrolled in randomized adjuvant chemotherapy trial. reported various recreational activities approximately 6 months after completion therapy were observed for recurrence or death. To minimize bias by occult recurrence, we excluded who experienced died within 90 days their assessment. Results Compared engaged less than three metabolic equivalent task (MET) -hours per week activity, adjusted hazard ratio disease-free survival was 0.51 (95% CI, 0.26 to 0.97) 18 26.9 MET-hours 0.55 0.33 0.91) 27 more week. The P trend .01. Postdiagnosis associated similar ...

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