Physiopathology of Colorectal Metastasis

作者: Cristiano Ferrario , Mark Basik

DOI: 10.1007/978-90-481-8833-8_2

关键词:

摘要: Colorectal metastatic disease is ultimately responsible for almost all of the mortality resulting from colorectal cancer. The spread cancer to ‘vital’ target organs such as liver and lung compromises normal physiology usually leads organ failure death. also spreads other, less bone peritoneum, whose diminished function may lead significant morbidity during course disease. In this chapter, we will discuss mechanisms patterns sites, how these metastases affect physiology, what factors progression in different sites.

参考文章(138)
María Elena Martínez, Primary prevention of colorectal cancer: lifestyle, nutrition, exercise. Recent results in cancer research. ,vol. 166, pp. 177- 211 ,(2005) , 10.1007/3-540-26980-0_13
J. P. Sleeman, The Lymph Node as a Bridgehead in the Metastatic Dissemination of Tumors Recent Results in Cancer Research. ,vol. 157, pp. 55- 81 ,(2000) , 10.1007/978-3-642-57151-0_6
Katrien Vekemans, Filip Braet, Structural and functional aspects of the liver and liver sinusoidal cells in relation to colon carcinoma metastasis World Journal of Gastroenterology. ,vol. 11, pp. 5095- 5102 ,(2005) , 10.3748/WJG.V11.I33.5095
Adrian L. Harris, Hypoxia — a key regulatory factor in tumour growth Nature Reviews Cancer. ,vol. 2, pp. 38- 47 ,(2002) , 10.1038/NRC704
A Pierce, M Lyon, I.N. Hampson, G.J. Cowling, J.T. Gallagher, Molecular cloning of the major cell surface heparan sulfate proteoglycan from rat liver. Journal of Biological Chemistry. ,vol. 267, pp. 3894- 3900 ,(1992) , 10.1016/S0021-9258(19)50610-X
A.B. Al-Mehdi, K. Tozawa, A.B. Fisher, L. Shientag, A. Lee, R.J. Muschel, Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis. Nature Medicine. ,vol. 6, pp. 100- 102 ,(2000) , 10.1038/71429
D. Mutter, A. Hajri, V. Tassetti, C. Solis-Caxaj, M. Aprahamian, J. Marescaux, Increased tumor growth and spread after laparoscopy vs laparotomy: influence of tumor manipulation in a rat model. Surgical Endoscopy and Other Interventional Techniques. ,vol. 13, pp. 365- 370 ,(1999) , 10.1007/S004649900991
Lola M. Reid, Isabel Zvibel, James D'Olimpio, Ralph Doerr, Diana Chiuten, Clonal growth of tumors on tissue-specific biomatrices and correlation with organ site specificity of metastases. Cancer Research. ,vol. 49, pp. 384- 392 ,(1989)
Joseph S. Palumbo, Kathryn E. Talmage, Jessica V. Massari, Christine M. La Jeunesse, Matthew J. Flick, Keith W. Kombrinck, Markéta Jirousková, Jay L. Degen, Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell–mediated elimination of tumor cells Blood. ,vol. 105, pp. 178- 185 ,(2005) , 10.1182/BLOOD-2004-06-2272
Peter Gassmann, Joerg Haier, The tumor cell–host organ interface in the early onset of metastatic organ colonisation Clinical & Experimental Metastasis. ,vol. 25, pp. 171- 181 ,(2008) , 10.1007/S10585-007-9130-6