Effect of screening and adjuvant therapy on mortality from breast cancer

作者: Donald A. Berry , Kathleen A. Cronin , Sylvia K. Plevritis , Dennis G. Fryback , Lauren Clarke

DOI: 10.1056/NEJMOA050518

关键词:

摘要: BACKGROUND We used modeling techniques to assess the relative and absolute contributions of screening mammography adjuvant treatment reduction in breast-cancer mortality United States from 1975 2000. METHODS A consortium investigators developed seven independent statistical models incidence mortality. All groups same sources obtain data on use mammography, treatment, benefits with respect rate death breast cancer. RESULTS The proportion total cancer attributed varied 28 65 percent (median, 46 percent), contributing rest. variability across contribution was larger than it for reflecting greater uncertainty associated estimating benefit screening. CONCLUSIONS Seven showed that both have helped reduce States.

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