Novel dicarboxylic acid derivatives

作者: Jignesh K Jivani , Bhavesh M. Panchal , Biswajit Samanta , Jeanne-Marie Lecomte , Marc Capet

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摘要: The present patent application concerns new compounds of formula (I): displaying agonistic activity at sphingosine-1-phosphate (S1P) receptors, their process preparation and use as immunosuppressive agents.

参考文章(15)
Philip M. Sher, Benzo 1,3 dioxole derivatives ,(1994)
Joseph W. Epstein, Feng L. Qing, Gary H. Birnberg, Beta3 -adrenergic agents and their use in pharmaceutical compositions ,(1993)
Minu D. Dutia, Joseph W. Epstein, Gary H. Birnberg, Thomas H. Claus, Elwood E. Largis, β3 -adrenergic agents, benzodioxole dicarboxylates and their use in pharmaceutical compositions ,(1995)
U. Denninger, J.J. Schneider, G. Wilke, R. Goddard, R. Krömer, C. Krüger, Transition metal complexes Journal of Organometallic Chemistry. ,vol. 459, pp. 349- 357 ,(1993) , 10.1016/0022-328X(93)86088-Y
George A. Doherty, Edward M. Scolnick, Richard Hajdu, Jeffrey J. Hale, Zhen Li, Sander G. Mills, Michael J. Forrest, Suzanne M. Mandala, Hugh Rosen, Selective s1p1/edg1 receptor agonists ,(2003)
Paul William Glue, Peter C. Hiestand, Carolyn Ann Foster, Sphingosine-1-phosphate receptor agonists in the treatment of demyelinating disorders ,(2003)
Suren Husinec, Ivan Juranic, Antonia Llobera, Alexander E. A. Porter, Bis(methoxycarbonyl)carbene Insertion into N-H Bonds: A Facile Route to N-Substituted Aminomalonic Esters Synthesis. ,vol. 1988, pp. 721- 723 ,(1988) , 10.1055/S-1988-27687
Jeffrey J. Hale, George Doherty, Leslie Toth, Sander G. Mills, Richard Hajdu, Carol Ann Keohane, Mark Rosenbach, James Milligan, Gan-Ju Shei, Gary Chrebet, James Bergstrom, Deborah Card, Michael Forrest, Shu-Yu Sun, Sarah West, Huijuan Xie, Naomi Nomura, Hugh Rosen, Suzanne Mandala, Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists Bioorganic & Medicinal Chemistry Letters. ,vol. 14, pp. 3501- 3505 ,(2004) , 10.1016/J.BMCL.2004.04.070
Michael S. Malamas, Fuk-Wah Sum, Aranapakam M. Venkatesan, George T. Grosu, Adam M. Gilbert, Gerardo D. Francisco, Substituted 1,3-benzodioxoles ,(1997)