Heparin-Based Hydrogel as a Matrix for Encapsulation and Cultivation of Primary Hepatocytes

作者: Mihye Kim , Ji Youn Lee , Caroline N. Jones , Alexander Revzin , Giyoong Tae

DOI: 10.1016/J.BIOMATERIALS.2010.01.068

关键词:

摘要: … important liver signaling molecule - into the hydrogel. HGF release from heparin hydrogel matrix was analyzed using enzyme linked immunoassay (ELISA) and was shown to occur in a …

参考文章(64)
James C. Y. Dunn, Martin L. Yarmush, Hans G. Koebe, Ronald G. Tompkins, Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. The FASEB Journal. ,vol. 3, pp. 174- 177 ,(1989) , 10.1096/FASEBJ.3.2.2914628
Linda K. Hansen, Joshua Wilhelm, John T. Fassett, Regulation of hepatocyte cell cycle progression and differentiation by type I collagen structure. Current Topics in Developmental Biology. ,vol. 72, pp. 205- 236 ,(2005) , 10.1016/S0070-2153(05)72004-4
S. N. Bhatia, U. J. Balis, M. L. Yarmush, M. Toner, Effect of cell–cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells The FASEB Journal. ,vol. 13, pp. 1883- 1900 ,(1999) , 10.1096/FASEBJ.13.14.1883
Francois Berthiaume, Prabhas V. Moghe, Mehmet Toner, Martin L. Yarmush, Effect of extracellular matrix topology on cell structure, function, and physiological responsiveness: hepatocytes cultured in a sandwich configuration. The FASEB Journal. ,vol. 10, pp. 1471- 1484 ,(1996) , 10.1096/FASEBJ.10.13.8940293
Takehisa Ishii, Maki Sato, Keiko Sudo, Masayuki Suzuki, Hiroshi Nakai, Tadashi Hishida, Takuro Niwa, Kohei Umezu, Satoshi Yuasa, Hepatocyte Growth Factor Stimulates Liver Regeneration and Elevates Blood Protein Level in Normal and Partially Hepatectomized Rats Journal of Biochemistry. ,vol. 117, pp. 1105- 1112 ,(1995) , 10.1093/OXFORDJOURNALS.JBCHEM.A124814
Won Il Choi, Mihye Kim, Giyoong Tae, Young Ha Kim, Sustained release of human growth hormone from heparin-based hydrogel. Biomacromolecules. ,vol. 9, pp. 1698- 1704 ,(2008) , 10.1021/BM701391B
Sihong Wang, Deepak Nagrath, Pohun C. Chen, François Berthiaume, Martin L. Yarmush, Three-dimensional primary hepatocyte culture in synthetic self-assembling peptide hydrogel. Tissue Engineering Part A. ,vol. 14, pp. 227- 236 ,(2008) , 10.1089/TEA.2007.0143
Giyoong Tae, Yang-Jung Kim, Won-Il Choi, Mihye Kim, Patrick S. Stayton, Allan S. Hoffman, Formation of a Novel Heparin-Based Hydrogel in the Presence of Heparin-Binding Biomolecules Biomacromolecules. ,vol. 8, pp. 1979- 1986 ,(2007) , 10.1021/BM0701189
Fan Yang, Christopher G Williams, Dong-an Wang, Hyukjin Lee, Paul N Manson, Jennifer Elisseeff, None, The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells. Biomaterials. ,vol. 26, pp. 5991- 5998 ,(2005) , 10.1016/J.BIOMATERIALS.2005.03.018
Andrew J. Putnam, David J. Mooney, Tissue engineering using synthetic extracellular matrices. Nature Medicine. ,vol. 2, pp. 824- 826 ,(1996) , 10.1038/NM0796-824