Intervention strategies for emerging viruses: use of antivirals

摘要: Today, small molecule antiviral drugs are available for the treatment of infections with herpesviruses, HIV, HBV and HCV as well influenza viruses. Ribavirin, a broad-spectrum (but aspecific) antiviral, has been approved respiratory syncytial virus, Lassa virus. Yet, many other viruses that cause life-threatening [most which considered emerging and/or neglected] there no available. Ideally, potent (i.e., pan-genus or pan-family virus activity) should be developed whereby one drug could used number such viral infections. We here review recent evolutions in search inhibitors neglected RNA