Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses

作者: Mathias Ehrich , Anders Olof Herman Nygren

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摘要: Provided are compositions and processes that utilize genomic regions differentially methylated between a mother her fetus to separate, isolate or enrich fetal nucleic acid from maternal sample. The described herein useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuplodies.

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