Hepatitis E virus and related viruses in wild, domestic and zoo animals: A review

摘要: Hepatitis E is a human disease mainly characterized by acute liver illness, which caused infection with the hepatitis virus (HEV). Large outbreaks have been described in developing countries; however, also increasingly recognized industrialized countries. Mortality rates up to 25% for pregnant women during In addition, chronic courses could be observed immunocompromised transplant patients. Whereas HEV genotypes 1 and 2 are confined humans, 3 4 found animals can zoonotically transmitted humans. Domestic pig wild boar represent most important reservoirs these genotypes. A distinct subtype of genotype has repeatedly detected rabbits few Recently, 7 identified dromedary camels an patient. The reservoir get infected without showing any clinical symptoms. Besides well-known animal reservoirs, HEV-specific antibodies and/or genome or HEV-related viruses many other species, including primates, mammals birds. particular, infections documented domestic, wildlife zoo species. cases, presence explained spillover infections, but risk transmission through contact humans cannot excluded. This review gives general overview on pathways It particularly focuses reported serological molecular evidence wild, domestic viruses. role discussed.