Management of seminoma with bulky abdominal disease.

摘要: Thirty-three cases of seminoma with palpable abdominal disease were treated at the Cancer Control Agency B.C. between 1948 and 1983. Twenty-three had confined to abdomen (Stage IIB), eight simultaneous involvement mediastinal supraclavicular nodes IIIB) two bone or pulmonary metastases IV). Five 10-year disease-specific actuarial survivals for whole group 87% 81%, respectively. Corresponding relapse-free survival was 64%. Of twenty-three IIB cases, 15 primary treatment radiation only, prophylactic mediastinal/supraclavicular radiation. Although relapse in more common receiving unchanged. For entire group, 5- 91% 84%, respectively, corresponding 74%. The IIIB patients primarily Four relapsed, all extranodal sites. Two these died disease. Both Stage IV required chemotherapy long-term control. can be radiation, but alone is inadequate when bulky associated supradiaphragmatic lymphatic spread hematogenous metastases.