Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015-2017.

作者: Helene M. De Nys , Placide Mbala Kingebeni , Alpha K. Keita , Christelle Butel , Guillaume Thaurignac

DOI: 10.3201/EID2412.180740

关键词:

摘要: To clarify the role of bats in ecology Ebola viruses, we assessed prevalence virus antibodies a large-scale sample collected during 2015-2017 from countries Africa that have had previous outbreaks (Guinea, Democratic Republic Congo) or are at high risk for (Cameroon). We analyzed 4,022 blood samples >12 frugivorous and 27 insectivorous species; 2-37 (0.05%-0.92%) were seropositive Zaire 0-30 (0%-0.75%) Sudan viruses. observed 1 bat genus 6 species. Certain species widespread across serologic evidence No viral RNA was detected subset tested (n = 665). Ongoing surveillance other potential animal reservoirs required to predict prepare future outbreaks.

参考文章(46)
Biao He, Yun Feng, Hailin Zhang, Lin Xu, Weihong Yang, Yuzhen Zhang, Xingyu Li, Changchun Tu, Filovirus RNA in Fruit Bats, China. Emerging Infectious Diseases. ,vol. 21, pp. 1675- 1677 ,(2015) , 10.3201/EID2109.150260
David M Irwin, Thomas D Kocher, Allan C Wilson, None, Evolution of the cytochrome b gene of mammals. Journal of Molecular Evolution. ,vol. 32, pp. 128- 144 ,(1991) , 10.1007/BF02515385
E. Leroy, J. P. Gonzalez, X. Pourrut, Ebolavirus and Other Filoviruses Current Topics in Microbiology and Immunology. ,vol. 315, pp. 363- 387 ,(2007) , 10.1007/978-3-540-70962-6_15
Megan Jones, Amy Schuh, Brian Amman, Tara Sealy, Sherif Zaki, Stuart Nichol, Jonathan Towner, Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera Viruses. ,vol. 7, pp. 3420- 3442 ,(2015) , 10.3390/V7072779
Siv Aina J. Leendertz, Jan F. Gogarten, Ariane Düx, Sebastien Calvignac-Spencer, Fabian H. Leendertz, Assessing the Evidence Supporting Fruit Bats as the Primary Reservoirs for Ebola Viruses Ecohealth. ,vol. 13, pp. 18- 25 ,(2016) , 10.1007/S10393-015-1053-0
Amy T Gilbert, AR Fooks, DTS Hayman, DL Horton, T Müller, R Plowright, AJ Peel, R Bowen, JLN Wood, J Mills, AA Cunningham, CE Rupprecht, None, Deciphering serology to understand the ecology of infectious diseases in wildlife. Ecohealth. ,vol. 10, pp. 298- 313 ,(2013) , 10.1007/S10393-013-0856-0
T. D. Kocher, W. K. Thomas, A. Meyer, S. V. Edwards, S. Paabo, F. X. Villablanca, A. C. Wilson, DYNAMICS OF MITOCHONDRIAL DNA EVOLUTION IN ANIMALS: AMPLIFICATION AND SEQUENCING WITH CONSERVED PRIMERS Proceedings of the National Academy of Sciences of the United States of America. ,vol. 86, pp. 6196- 6200 ,(1989) , 10.1073/PNAS.86.16.6196
Hirohito Ogawa, Hiroko Miyamoto, Eri Nakayama, Reiko Yoshida, Ichiro Nakamura, Hirofumi Sawa, Akihiro Ishii, Yuka Thomas, Emiko Nakagawa, Keita Matsuno, Masahiro Kajihara, Junki Maruyama, Naganori Nao, Mieko Muramatsu, Makoto Kuroda, Edgar Simulundu, Katendi Changula, Bernard Hang'Ombe, Boniface Namangala, Andrew Nambota, Jackson Katampi, Manabu Igarashi, Kimihito Ito, Heinz Feldmann, Chihiro Sugimoto, Ladslav Moonga, Aaron Mweene, Ayato Takada, None, Seroepidemiological Prevalence of Multiple Species of Filoviruses in Fruit Bats (Eidolon helvum) Migrating in Africa Journal of Infectious Diseases. ,vol. 212, pp. S101- S108 ,(2015) , 10.1093/INFDIS/JIV063
Eric M. Leroy, Brice Kumulungui, Xavier Pourrut, Pierre Rouquet, Alexandre Hassanin, Philippe Yaba, André Délicat, Janusz T. Paweska, Jean-Paul Gonzalez, Robert Swanepoel, Fruit bats as reservoirs of Ebola virus Nature. ,vol. 438, pp. 575- 576 ,(2005) , 10.1038/438575A
Xavier Pourrut, Marc Souris, Jonathan S Towner, Pierre E Rollin, Stuart T Nichol, Jean-Paul Gonzalez, Eric Leroy, Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus BMC Infectious Diseases. ,vol. 9, pp. 159- 159 ,(2009) , 10.1186/1471-2334-9-159