作者: Benny Antony , Graeme Jones , Alison Venn , Flavia Cicuttini , Lyn March
DOI: 10.1002/ACR.22588
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摘要: Objective: We aimed to determine the associations between childhood physical performance measures and tibial cartilage volume bone area in adults 25 years later. Methods: Participants ( n = 330, ages 31–41 years, female 47%) were selected from Australian Schools Health Fitness Survey of 1985. The participants underwent T1-weighted fat-suppressed magnetic resonance imaging (MRI) their knees. Tibial measured MRI. Childhood measures, including work capacity at 170 beats per minute (PWC ), leg strength, number sit-ups, long-run, short-run PWC strength repeated after 20 adulthood. Linear regression analysis was used association with volume. Results: There consistent positive all β = 0.38 cm 2 10 watts, 95% confidence interval [95% CI] 0.15, 0.60), short-run, sit-ups adult medial total area. Similarly, there an After further adjustment for area, = 0.08 3 CI 0.02, 0.10) decreased magnitude but remained significant. Conclusion: Childhood especially , associated knee appeared be partially mediated by This suggests can independently influence structures.