Childhood Physical Performance Measures and Adulthood Knee Cartilage Volume and Bone Area: A 25‐Year Cohort Study

作者: Benny Antony , Graeme Jones , Alison Venn , Flavia Cicuttini , Lyn March

DOI: 10.1002/ACR.22588

关键词:

摘要: Objective: We aimed to determine the associations between childhood physical performance measures and tibial cartilage volume bone area in adults 25 years later. Methods: Participants ( n  = 330, ages 31–41 years, female 47%) were selected from Australian Schools Health Fitness Survey of 1985. The participants underwent T1-weighted fat-suppressed magnetic resonance imaging (MRI) their knees. Tibial measured MRI. Childhood measures, including work capacity at 170 beats per minute (PWC ), leg strength, number sit-ups, long-run, short-run PWC strength repeated after 20 adulthood. Linear regression analysis was used association with volume. Results: There consistent positive all β  = 0.38 cm 2 10 watts, 95% confidence interval [95% CI] 0.15, 0.60), short-run, sit-ups adult medial total area. Similarly, there an After further adjustment for area,  = 0.08 3 CI 0.02, 0.10) decreased magnitude but remained significant. Conclusion: Childhood especially , associated knee appeared be partially mediated by This suggests can independently influence structures.

参考文章(39)
R. P. Heaney, S. Abrams, B. Dawson-Hughes, A. Looker, A. Looker, R. Marcus, V. Matkovic, C. Weaver, Peak bone mass Osteoporosis International. ,vol. 11, pp. 985- 1009 ,(2001) , 10.1007/S001980070020
C. Ding, J. Martel-Pelletier, J.-P. Pelletier, F. Abram, J.-P. Raynauld, F. Cicuttini, G. Jones, Two-year prospective longitudinal study exploring the factors associated with change in femoral cartilage volume in a cohort largely without knee radiographic osteoarthritis Osteoarthritis and Cartilage. ,vol. 16, pp. 443- 449 ,(2008) , 10.1016/J.JOCA.2007.08.009
Felix Eckstein, Martin Hudelmaier, September Cahue, Meredith Marshall, Leena Sharma, Medial-to-lateral ratio of tibiofemoral subchondral bone area is adapted to alignment and mechanical load. Calcified Tissue International. ,vol. 84, pp. 186- 194 ,(2009) , 10.1007/S00223-008-9208-4
Shreyasee Amin, Kristin Baker, Jingbo Niu, Margaret Clancy, Joyce Goggins, Ali Guermazi, Mikayel Grigoryan, David J. Hunter, David T. Felson, Quadriceps Strength and the Risk of Cartilage Loss and Symptom Progression in Knee Osteoarthritis Arthritis & Rheumatism. ,vol. 60, pp. 189- 198 ,(2009) , 10.1002/ART.24182
C G Peterfy, C F van Dijke, D L Janzen, C C Glüer, R Namba, S Majumdar, P Lang, H K Genant, Quantification of articular cartilage in the knee with pulsed saturation transfer subtraction and fat-suppressed MR imaging: optimization and validation. Radiology. ,vol. 192, pp. 485- 491 ,(1994) , 10.1148/RADIOLOGY.192.2.8029420
F. Eckstein, S. Faber, R. Mühlbauer, J. Hohe, K.-H. Englmeier, M. Reiser, R. Putz, Functional adaptation of human joints to mechanical stimuli. Osteoarthritis and Cartilage. ,vol. 10, pp. 44- 50 ,(2002) , 10.1053/JOCA.2001.0480
Harpal K. Gahunia, Kenneth P.H. Pritzker, Effect of exercise on articular cartilage. Orthopedic Clinics of North America. ,vol. 43, pp. 187- 199 ,(2012) , 10.1016/J.OCL.2012.03.001
Changhai Ding, Patrick Garnero, Flavia Cicuttini, Fiona Scott, Helen Cooley, Graeme Jones, Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen breakdown. Osteoarthritis and Cartilage. ,vol. 13, pp. 198- 205 ,(2005) , 10.1016/J.JOCA.2004.11.007
Graeme Jones, Michael Glisson, Kristen Hynes, Flavia Cicuttini, Sex and site differences in cartilage development: A possible explanation for variations in knee osteoarthritis in later life Arthritis & Rheumatism. ,vol. 43, pp. 2543- 2549 ,(2000) , 10.1002/1529-0131(200011)43:11<2543::AID-ANR23>3.0.CO;2-K