Special Issue on Global Cancer Medicine

摘要: A half century ago, 70 cancer professionals gathered in a conference room Philadelphia what would mark the first scientific meeting of American Society Clinical Oncology (ASCO). At time, it have been impossible to predict achievements prevention, care, and treatment that made United States other developed countries, resulting significant improvements survival from quality life. Many advances cataloged this journal, now widely read as predominant oncology publication. Much world’s burden cancermortality occurs not world, but developing Special Series Journal (JCO), editorial board has granted us opportunity focus on ever-increasing parts world often thought be plagued only with infectious diseases, or so-called diseases poverty. What is less well documented, certainly frequently at nucleus dialogue, diversity biology around how countries partners are responding major global cancer. Globally, 2013, an estimated 15million patientswere newly diagnosed cancer, 8.2 million people died. That year alone, almost amillionwomendiedof breast disease that, if caught early stages, wenowunderstand largely treatable andoften curable. Today theUnited States, despite consistently high incidence rate, diagnosis most accompanied by set therapeutic plans prolong life even cure patient, approximately 70%of patients can expect live for more than 5 years. Sowhere 8.2million dying each year?Many deaths still do occur among two thirds world. Doubly encumbered sparse overtaxed health care workforce both communicable noncommunicable face extreme barriers addressing needs Not facilities few far between low-income where they exist, unaffordable much population. However, one our authors, Paul Farmer, reminded many conversations, “We three.” The vast expanse knowledge, tools, clinical inwealthier tremendous impact applied partnership currently struggling establish ormaintain nascent research, programs. In vein, we solicited articles authors who engaged control across number disciplines, including biology, public health, medical education, policy, delivery science. It aim through community continues expand its purview all those need no matter patient happens live. series opens article imperatives bringing poor, weaving history HIV access movement decades ago. Barriers high-quality resultant poor outcomes were examined low-, middle-, high-income exploring commonalities (the effects poverty, instance), differences these settings, using Kenya, Brazil, examples. Structural detection timely explored depth Cazap et al. spectrum services required long, pathology radiation therapy illuminate challenges practical solutions specific points along chain countries. Developing andmaintaining strong infrastructures require human resource capacity run, manage, optimize them. Authors working Kenya’s rural west describe education training care. Delivering resource-constrained settings provides multitude unique nonconventional innovative approaches. Continuous evaluation results identification gaps, together targeted interventions improve safety efficacy requires data collection reporting, Rwanda calls integration implementation science into medicine. Global pediatric area receives attention should. Although childhood common adults, potential rates high, cured long productive will tragically lost available. editors asked some leading experts their experience respond children Another oft-overlooked international pain management. Given late-stage presentation palliative supportive essential medicines beenmade recent years, little affordable medicines. Shulman al share methodologies collaboration WHO, which increased Essential Medicines List. ASCO played important role medicine over years so recently. Chronicling