Oxytetracycline and penicillin-G residues in cattle slaughtered in south-western Nigeria: Implications for livestock disease management and public health

摘要: After the discovery of indiscriminate antibiotic use in ready-for-slaughter cattle south-western Nigeria, 90 tissue samples from randomly selected slaughtered were evaluated for oxytetracycline and penicillin-G residues using high performance liquid chromatography data analysed by one-way Analysis variance (ANOVA). The findings revealed (kidney: 9.47 µ/kg ± 3.24 µ/kg; liver: 12.73 4.39 muscle: 16.17 5.52 µ/kg) 6.27 2.46 8.5 2.80 11.67 2.94 all tissues screened. Significantly levels (oxytetracycline: F = 16.77; penicillin-G: 29.38) were, however, found muscles, followed liver then kidney – confirming recent administration to animals before slaughter. dietary intakes through screened 0.024% (oxytetracycline) 0.017% (penicillin-G) acceptable daily intake (ADI). Although concentrations below maximum residue limits despite these antibiotics slaughter, lower are suggestive probable low dosages often administered those involved antibiotics. This therefore raises serious concerns livestock industry as well human health, given resultant emergence spread resistant strains bacterial pathogens that could ensue prolonged Additionally, notwithstanding, plausible exposure other food sources is a cause concern. Since antimicrobial misuse its consequent effects not just problem limited Nigeria but also concern sub-Saharan Africa, need national international stakeholder intervention emphasised.