Mucosal and Acquired Immunity in Giardiasis and Its Relation to Diarrhea and Malabsorption

作者: N. K. Ganguly , R. C. Mahajan

DOI: 10.1007/978-1-4612-3508-8_21

关键词:

摘要: Giardiasis is a relatively common intestinal protozoal infection in man and animals (2,46). Several reports indicate that the more immunodeficient (3,47) malnourished (44) hosts individuals with tendency to feco-oral transmission, such as infants day-care nurseries (8) or homosexuals (52). The disease may occur both epidemic endemic forms (40,64). clinical spectrum of ranges from an entirely asymptomatic mild, self-limiting illness, chronic diarrhea without malabsorption (34,65). Despite ubiquitous prevalence parasites, pathophysiology remains obscure. Therefore this chapter reviews possible mechanism increasingly important infection.

参考文章(57)
A M Tomkins, S G Wright, Quantification of the lymphocytic infiltrate in jejunal epithelium in giardiasis. Clinical and Experimental Immunology. ,vol. 29, pp. 408- 412 ,(1977)
E.A. Meyer, S. Radulescu, Giardia and Giardiasis Advances in Parasitology Volume 17. ,vol. 17, pp. 1- 47 ,(1979) , 10.1016/S0065-308X(08)60548-5
Ian C. Roberts-Thomson, Graham F. Mitchell, Giardiasis in mice. I. Prolonged infections in certain mouse strains and hypothymic (nude) mice. Gastroenterology. ,vol. 75, pp. 42- 46 ,(1978) , 10.1016/0016-5085(78)93761-7
Robert E. Black, Aubert C. Dykes, Susanne P. Sinclair, Joy G. Wells, Giardiasis in day-care centers: evidence of person-to-person transmission. Pediatrics. ,vol. 60, pp. 486- 491 ,(1977)
Joel D. Levinson, Lawrence J. Nastro, Giardiasis with total villous atrophy. Gastroenterology. ,vol. 74, pp. 271- 275 ,(1978) , 10.1016/0016-5085(78)90809-0
William A. Hartong, William K. Gourley, Constantine Arvanitakis, Giardiasis: clinical spectrum and functional--structural abnormalities of the small intestinal mucosa. Gastroenterology. ,vol. 77, pp. 61- 69 ,(1979) , 10.1016/S0016-5085(79)80011-6
Phillip D. Smith, Frances D. Gillin, William M. Spira, Theodore E. Nash, Chronic Giardiasis: Studies on Drug Sensitivity, Toxin Production, and Host Immune Response Gastroenterology. ,vol. 83, pp. 797- 803 ,(1982) , 10.1016/S0016-5085(82)80008-5
T.K. Saha, T.K. Ghosh, Invasion of Small Intestinal Mucosa by Giardia lamblia in Man Gastroenterology. ,vol. 72, pp. 402- 405 ,(1977) , 10.1016/S0016-5085(77)80247-3