Approaches to salivary cortisol collection and analysis in infants.

摘要: Salivary cortisol is becoming more commonly utilized as a biologic marker of stress in observational studies and intervention research. However, its use with infants (12 months age or younger) less widespread poses some special challenges to researchers. In order decide on the most suitable collection procedure for salivary infants, number criteria should be considered. This article will aid investigators interested integrating measurement into their research by presenting (1) an overview patterns secretion infancy including development diurnal rhythm response stress; (2) comparison used approaches collecting samples cotton rope, syringe aspiration technique, filter paper, hydrocellulose microsponge, Salimetrics children's swab; (3) discussion factors contributing heightened variability how these can limited; (4) analytical issues associated measurement; (5) examples consider when choosing saliva sampling method lab conducting assays.