Hippocampal subfields and decline in activities of daily living in Alzheimer's disease and dementia with Lewy bodies.
作者： Miguel Germán Borda , Alberto Jaramillo-Jimenez , Diego A Tovar-Rios , Daniel Ferreira , Elkin Garcia-Cifuentes
关键词:
摘要: Background: Hippocampal atrophy is presented in Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). Cognition, dual-tasks, muscular function, goal-related behaviors neuropsychiatric symptoms are linked to hippocampal volumes may lead functional decline activities of daily living. We examined the association between baseline subfield (HSv) mild AD DLB, decline. Materials & methods: 12 HSv were computed from structural magnetic resonance images using Freesurfer 6.0 segmentation. Functional was assessed rapid disability rating scale score. Linear regressions conducted. Results: In AD, smaller bilaterally. However, not associated Conclusion: does depend on DLB.
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