Age-dependency of sensitization to aero-allergens in asthmatics.

摘要: Skin reactivity (intracutaneous test) to histamine and allergens was studied cross-sectionally in a Dutch asthmatic patient population from childhood old age (4-75 years). It found that the skin rose significantly (p less than 0.05) during childhood, higher 10-15-year group, constant between 20 75 years of age. The mean wheal index (histamine ratio) all decreased after 25 for grass pollen house-dust mite 15 other allergens. prevalence positive test with age, except pollen. During indoor allergens, cat dander mite, were most important, while sensitivity an outdoor allergen, pollen, increased markedly. At ages important allergen. After every allergen declines. Cladosporium unexpectedly high (10-40%). can be concluded declines degree sensitization asthmatics peaked groups 40 developed earlier