Differences in Ultrasonic Vocalizations between Wild and Laboratory California Mice (Peromyscus californicus)

摘要: Background: Ultrasonic vocalizations (USVs) emitted by muroid rodents, including laboratory mice and rats, are used as phenotypic markers in behavioral assays biomedical research. Interpretation of these USVs depends on understanding the significance USV production rodents wild. However, there has never been a study rodent ultrasound function wild comparisons produced lacking to date. Here, we report first comparison captive recorded from same species, Peromyscus californicus. Methodology Principal Findings: We standard recording techniques measure California (Peromyscus Genetic Stock Center, SC, USA) (Hastings Natural History Reserve, CA, USA). To determine which mouse was vocalizing, remote sensing method that 12-microphone acoustic localization array coupled with automated radio telemetry all resident californicus area array. types motifs. were 2–8 kHz higher median frequency significantly more variable in than mice. Significance: The similarity overall form demonstrates is not an artifact captivity. Our validates widespread use indicators but highlights particular characteristics may reflect natural conditions.