Na2EDTA Enhances the Absorption of Iron and Zinc from Fortified Rice Flour in Sri Lankan Children

摘要: Rice flour was proposed as a vehicle for iron and zinc fortification in Sri Lanka. Although widely consumed, rice has not been evaluated fortified food, the absorption of minerals including from this is unknown. Determination bioavailability these nutrients critical step before commencing program. We randomly divided 53 Lankan schoolchildren ages 6-10 y into 4 groups that consumed local dish prepared with 25 g labeled one following: 1) (58)FeSO(4) 2) + Na(2)EDTA 3) (67)ZnO or, 4) (67)ZnO. The levels were 60 mg/kg; also contained folate at 2 mg/kg each group. added Fe:Na(2)EDTA, 1:1 molar ratio. A total 48 children completed trial. Absorption (58)Fe meal significantly greater (P < 0.01) administered FeSO(4) (4.7 +/- 3.6%) than those without (2.2 1.3%). Fractional 13.5 6.0% group 8.8 2.0% = 0.037). low, our results demonstrated benefit using to improve both absorption. conclude feasible, although additional strategies such dephytinization or an increase level should be considered obtain higher proportion daily requirement absorbed zinc.