Is uric acid a surrogate and additional component of incident metabolic syndrome, insulin resistance among inactive Central Africans?

摘要: Abstract Objective To assess the patterns underlying co-occurrence of components metabolic syndrome defined by IDF criteria and insulin resistance using Factor Analysis. Methods A 5-year patient clinic-based prospective randomized study active versus inactive was conducted among black Africans aged over 40 years at LOMO MEDICAL Center, Kinshasa, DRC. Results Among 282 patients, 1.7%, 12.7%, 2.8%, 15.9%, 10.9%, 15.9% patients were incidence type 2 diabetes, acute stroke, myocardial infarction, resistance, syndrome + insulin hyperuricemia. Male gender, physical inactivity, high Hs-CRP abdominal obesity independent predictors Obesity factor (hip circumference, BMI, WC), (HOMA index insulin), dysglycemia/dyslipidemia (glucose, LDL, HDL, total cholesterol, triglycerides) inflammation (Hs-CRP) identified explained a variance 79% on analysis in with resistance. In isolated syndrome, fat distribution, disorders (WC, triglycerides, glucose uric acid, HDL) blood pressure two factors explaining 55% model. Conclusion Uric acid may be considered as an additional component without