Is Hyperuricemia Another Facet of the Metabolic Syndrome

作者: Teh-Ling Liou , Ming-Wei Lin , Li-Chuan Hsiao , Ting-Ting Tsai , Wan-Leong Chan

DOI: 10.1016/S1726-4901(09)70186-8

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摘要: Background Hyperuricemia is commonly associated with obesity, glucose intolerance, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. The resemblance of the metabolic syndrome hyperuricemia has led to suggestion that a part syndrome. purpose this study examine contribution uric acid (UA) as an additional component in middle-aged men. Methods In total, 393 male participants, aged 45-60 years, were recruited from professional health evaluation program. Anthropometric measurements blood pressure (BP) taken after overnight fast. Fasting samples collected for glucose, UA, lipid profile. Logistic regression models fitted relationship between UA diagnosis Factor analysis was performed explore components Results significantly waist circumference (WC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), systolic BP, liver enzyme levels, but not levels. sensitivity (serum = 7.0 mg/dL) 58.0% specificity 55.3%. factor analysis, aggregated body mass index, WC, log TG, HDL-C factor. Systolic diastolic BP loaded on second separately. model explained similar proportion total variance (56.9%), did without (62.5%). Conclusion Our results suggest seems be insignificant. We propose might important facet understanding underlying structure

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