Uric acid: an additional component of metabolic syndrome?

作者: Wayne H.H. Sheu , Yao-Hsien Tseng

DOI: 10.1016/S1726-4901(09)70184-4

关键词:

摘要: The significance of metabolic syndrome in association with cardiovascular diseases has triggered extensive debate, and the number medical reports this area is increasing exponentially. One several controversial points whether 5 components (elevated glucose, higher triglyceride, lowered highdensity lipoprotein [HDL] cholesterol, central obesity, hypertension) syndrome, as proposed by Adult Treatment Panel III (ATP III) National Cholesterol Education Program (NCEP), are equally important. This debate even been challenged a new definition from International Diabetes Federation (IDF), which singled out obesity core syndrome. Another interesting point these adequately cover whole spectrum For example, vascular inflammation markers such highly sensitive C-reactive protein (CRP) have additional Metabolic group risk factors that predispose to disease. Many studies confirmed positive between hyperuricemia As matter fact, was reported one independent predictor future events an 11-year follow-up study Taiwan. link insulin resistance, major abnormality elucidated Facchini et al, who urinary uric acid clearance decreased proportion increases resistance normal volunteers. They attributed compensatory hyperinsulinemia subjects Uric Acid: An Additional Component Syndrome?

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