作者: M S Tallman , D Hakimian , J M Shaw , G S Lissner , E J Russell
DOI: 10.1200/JCO.1993.11.4.690
关键词:
摘要: PURPOSESince the only three cases of granulocytic sarcoma among patients with acute myeloid leukemia (AML) seen at our institution during last 12 years were each associated 8;21 translocation [t(8;21)], we sought to determine if this association is specific and more frequent than previously recognized.PATIENTS AND METHODSWe report AML t(8;21) who developed sarcomas, review world literature.RESULTSBetween 1980 1992, 53 French-American-British (FAB) M2 identified institution. Eight (15%) had t(8;21). Three these eight (38%) sarcoma. All received conventional intensive antileukemic chemotherapy yet short relapse-free survival durations. Several series that sarcomas occur in approximately 18% population, which four times expected incidence AML. Thirty-seven have been reported....