Handwriting analysis indicates spontaneous dyskinesias in neuroleptic naïve adolescents at high risk for psychosis.

摘要: Growing evidence suggests that movement abnormalities are a core feature of psychosis. One marker abnormality, dyskinesia, is result impaired neuromodulation dopamine in fronto-striatal pathways. The traditional methods for identifying include observer-based reports and force stability gauges. drawbacks these long training times raters, experimenter bias, large site differences instrumental apparatus, suboptimal reliability. Taking into account has guided the development better standardized more efficient procedures to examine through handwriting analysis software tablet. Individuals at risk psychosis showed significantly dysfluent pen movements (a proximal measure dyskinesia) task. Handwriting kinematics offers great advance over previous assessing which could clearly be beneficial understanding etiology