Smoking and tardive dyskinesia in male patients with chronic schizophrenia.

摘要: Interactions between smoking and movement disorders include the contrasting associations of more cigarette with reductions in Parkinson's disease increases tardive dyskinesia (TD) symptoms. Here we examine relationship TD a large sample inpatients schizophrenia. We used cross-sectional naturalistic methods to analyze prevalence severity neuroleptic-induced relation among 764 male chronic medicated meeting DSM-IV criteria for administered detailed questionnaire including general information, medical psychological conditions, behaviors. evaluated using abnormal involuntary scale (AIMS) psychopathology Positive Negative Syndrome Scale (PANSS). The main statistical analyses cross-tabulations by multivariate regression continuous measures (AIMS PANSS). found that did not significantly differ smokers (41%=237/578) non-smokers (37%=69/186). Secondary outcomes showed significant association AIMS total score age, duration illness hospitalization times. Thus, was associated Chinese schizophrenics, but consistent previous reports, older patients longer hospitalizations greater TD.