Sedation characteristics of melatonin and midazolam for premedication of adult patients undergoing cataract surgery under local anaesthesia

摘要: This prospective, double blind placebo controlled study is designed to compare the effects of sublingual melatonin versus midazolam for premedication adult patients scheduled undergo cataract surgery under local anaesthesia. Seventy five ASA1&2 ranged from 40-70 yr procedure were studied. Patients classified into 3 groups. Group 1 received midazolam, group 2 and placebo. in 0.5% solution 0.1mg/kg body weight. melatonin0.05mg/kg The control (saline).All drugs given 100 min before block. Sedation, anxiety orientation quantified 10, 30, 60 after 15, admission recovery room. One way ANOVA non-parametric Kurskal-wallis test statistical analysis. who with either or had significant decrease levels compared increase level sedation operation was noticed groups (p 0.05). Amnesia not both In conclusion, can be used effectively without hangover effect midazolam.