摘要: Melatonin is a neurohormone secreted by the pineal gland. It widely present in both plant and animal sources. In several countries, it sold over counter as tablets food supplement or additive. Currently, most often used to prevent jet lag induce sleep. has been being clinical trials with different therapeutic approaches. sedative, analgesic, anti-inflammatory, anti-oxidative chronobiotic effects. review, potential benefits of melatonin anaesthesia critical care are presented. This article aims review physiological properties how these could prove useful for applications perioperative management, pain medicine. The topic was handsearched from textbooks journals electronically PubMed, Google scholar using text words.
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core.ac.uk参考文章(12)
Promila Pandhi, Samir Malhotra, Girish Sawhney, The therapeutic potential of melatonin: a review of the science. MedGenMed : Medscape general medicine. ,vol. 6, pp. 46- ,(2004)
Russel J. Reiter, Dun-Xian Tan, Lorena Fuentes-Broto, Melatonin: a multitasking molecule. Progress in Brain Research. ,vol. 181, pp. 127- 151 ,(2010) , 10.1016/S0079-6123(08)81008-4
Michael Wilhelmsen, Ilda Amirian, Russel J. Reiter, Jacob Rosenberg, Ismail Gögenur, Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies. Journal of Pineal Research. ,vol. 51, pp. 270- 277 ,(2011) , 10.1111/J.1600-079X.2011.00895.X
Saleh A Al Obeidan, Samir M Al-Mansouri, Rana Altaf Ahmad, Abdulhamid Samarkandi, Sedation characteristics of melatonin and midazolam for premedication of adult patients undergoing cataract surgery under local anaesthesia Saudi Journal of Anaesthesia. ,vol. 1, pp. 6- ,(2007)
Mohamed Naguib, Phillip G. Schmid, Max T. Baker, The electroencephalographic effects of IV anesthetic doses of melatonin: comparative studies with thiopental and propofol. Anesthesia & Analgesia. ,vol. 97, pp. 238- 243 ,(2003) , 10.1213/01.ANE.0000065545.58026.23
Maurizia Capuzzo, Barbara Zanardi, Elisa Schiffino, Cosimetta Buccoliero, Daniela Gragnaniello, Stefano Bianchi, Raffaele Alvisi, Melatonin does not reduce anxiety more than placebo in the elderly undergoing surgery. Anesthesia & Analgesia. ,vol. 103, pp. 121- 123 ,(2006) , 10.1213/01.ANE.0000222476.62547.ED
Richard S. Bourne, Gary H. Mills, Melatonin: possible implications for the postoperative and critically ill patient Intensive Care Medicine. ,vol. 32, pp. 371- 379 ,(2006) , 10.1007/S00134-005-0061-X
Maria-Dolores Maldonado, Francisco Murillo-Cabezas, Juan-Ramón Calvo, Patricia-Judith Lardone, Dun-Xian Tan, Juan-Miguel Guerrero, Russell J. Reiter, Melatonin as pharmacologic support in burn patients: a proposed solution to thermal injury-related lymphocytopenia and oxidative damage. Critical Care Medicine. ,vol. 35, pp. 1177- 1185 ,(2007) , 10.1097/01.CCM.0000259380.52437.E9
Josephine Arendt, Melatonin: Characteristics, Concerns, and Prospects Journal of Biological Rhythms. ,vol. 20, pp. 291- 303 ,(2005) , 10.1177/0748730405277492
Maria de Lourdes V. Seabra, Magda Bignotto, Luciano R. Pinto Jr., Sergio Tufik, Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment. Journal of Pineal Research. ,vol. 29, pp. 193- 200 ,(2000) , 10.1034/J.1600-0633.2002.290401.X