Mathematical modelling of tumour-induced angiogenesis: network growth and structure.
作者： Mark Chaplain , Alexander Anderson
DOI: 10.1007/978-1-4419-8871-3_3
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摘要: Angiogenesis, the formation of blood vessels from a pre-existing vasculature,is process whereby capillary sprouts are formed in response to externally supplied chemical stimuli. The then grow and develop, driven initially by endothelial cell migration, organise themselves into branched, connected network. Subsequent proliferation near sprout-tips permits further extension capillaries ultimately completes process. Angiogenesis occurs during embryogenesis, wound healing, arthritis growth solid tumours.
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